In this podcast, the speaker discusses the varying effects of supplements such as Vitamin D and Vitamin C on the body's hormones. They mention that they have improved people's physiology by removing vitamin D and that the curve for hormone-like effects is long with Vitamin C.
Creatine supplementation has the greatest positive effects on individuals with low creatine, while having little to no effect on those with normal to high levels. It does not affect hormone production but can improve physical performance.