Chapter
The Relationship Between Genetic Variants, Gene Expression, and Disease
38:16 - 46:47 (08:31)
Exploring how genetic variants can have a small impact on genes but still impact the probability of disease, and the importance of studying gene expression to determine the best places to intervene to combat disease.
Clips
The podcast discusses the use of genetics in the identification of developmental genes and Mendelian disorders that have a strong genetic impact on disease.
38:16 - 43:33 (05:16)
Genetics
Summary
The podcast discusses the use of genetics in the identification of developmental genes and Mendelian disorders that have a strong genetic impact on disease.
ChapterThe Relationship Between Genetic Variants, Gene Expression, and Disease
Episode#133 – Manolis Kellis: Biology of Disease
PodcastLex Fridman Podcast
By coupling genetics with expression variation, we can identify the best places to intervene in disease treatment, even if the genetic variants have a weak effect on the disease-causing gene.
43:33 - 46:47 (03:14)
Genetics
Summary
By coupling genetics with expression variation, we can identify the best places to intervene in disease treatment, even if the genetic variants have a weak effect on the disease-causing gene.