goodlisten

Clip

The Importance of Acknowledging Strain Differences in Science
listen on Spotify
52:27 - 54:31 (02:04)

In a study on the effects of metformin supplementation on the lifespan of Fisher 344 rats, no significant lifespan extension was observed. While it's important to standardize dosage, it may be more effective to mix metformin into the animals' food rather than injecting them with it directly.

Similar Clips
The Canine Longevity Project is a study aiming to identify genetic factors associated with healthy aging in dogs.
21:06 - 22:43 (01:36)
listen on Spotify
Canine Longevity Project
Summary

The Canine Longevity Project is a study aiming to identify genetic factors associated with healthy aging in dogs. Pet owners interested in participating can speak to their veterinarian about the project and potentially prescribe a medication off-label under veterinary supervision.

Chapter
Early Intervention in Dogs: Treating Problems Before They Get Worse
Episode
#549: The Random Show — Biohacking, Tim’s COVID Experience, Holiday Gift Ideas, Favorite New Apps, Bad Science, Quarantine Delights, and a Small Dose of NFTs and DAOs
Podcast
The Tim Ferriss Show
The speaker shares that they have been working and talking with the FDA to develop a drug for animal health that requires FDA approval since the beginning, adding that a weight loss drug was unsuccessful in the animal health industry in the past.
44:59 - 47:04 (02:04)
listen on Spotify
Animal Health
Summary

The speaker shares that they have been working and talking with the FDA to develop a drug for animal health that requires FDA approval since the beginning, adding that a weight loss drug was unsuccessful in the animal health industry in the past.

Chapter
The route to getting aging pills approved by the FDA
Episode
This CEO Wants a Fountain of Youth for Dogs. Can We Be Next? Please?
Podcast
The Problem With Jon Stewart
Researchers have identified six or seven small molecules that could potentially extend the health span of dogs, including metformin and others that have shown evidence of beneficial effects on metabolic health and overall health.
54:01 - 56:27 (02:26)
listen on SpotifyListen on Youtube
Health span
Summary

Researchers have identified six or seven small molecules that could potentially extend the health span of dogs, including metformin and others that have shown evidence of beneficial effects on metabolic health and overall health.

Chapter
Longevity-Extending Compounds Worth Watching
Episode
#610: The Life-Extension Episode — Dr. Matt Kaeberlein on The Dog Aging Project, Rapamycin, Metformin, Spermidine, NAD+ Precursors, Urolithin A, Acarbose, and Much More
Podcast
The Tim Ferriss Show
Discover the efforts in mitigating heart failure in large dogs, with the study of other markers of health span also showing improvements in canine companions.
1:36:37 - 1:38:21 (01:43)
listen on Spotify
Dogs
Summary

Discover the efforts in mitigating heart failure in large dogs, with the study of other markers of health span also showing improvements in canine companions. However, limited funding and high costs make the research challenging.

Chapter
The Origins of Rapamycin
Episode
#517: Dr. Peter Attia on Longevity Drugs, Alzheimer's Disease, and the 3 Most Important Levers to Pull
Podcast
The Tim Ferriss Show
The use of anabolic androgenic steroids (AAS) can have negative effects on testosterone production, libido and adolescent development, as evidenced by case studies, although it's important not to overinterpret these anecdotal reports.
36:08 - 38:21 (02:13)
listen on SpotifyListen on Youtube
Androgenic Steroid Use