Hamilton Morris on Iboga, 5-MeO-DMT, The Power of Ritual, New Frontiers in Psychedelics, Excellent Problems to Solve, and More | Brought to you by Dry Farm Wines natural wines designed for fewer hangovers, LMNT electrolyte supplement, and Oura smart ring wearable for personalized sleep and health insights. More on all three below.Hamilton Morris (@HamiltonMorris) is a chemist, filmmaker, and science journalist. A graduate of The New School, he conducts chemistry research at The University of the Sciences in Philadelphia.Hamilton is the writer and director of the documentary series Hamilton’s Pharmacopeia, in which he explores the chemistry and traditions surrounding psychoactive drugs. His research has allowed him to study psychoactive plants, fungi, and chemicals, as well as the culture that surrounds them, in more than 30 countries, using an interdisciplinary approach that combines anthropology and chemistry.Hamilton’s recent republishing of a book on Bufo alvarius has, at the time of writing, raised more than $205,000 for Parkinson’s disease research.Please enjoy!This episode is brought to you by Dry Farm Wines. I’m a wine drinker, and I love a few glasses over meals with friends. That said, I hate hangovers. For the last few months, most of the wine in my house has been from Dry Farm Wines. Why? At least in my experience, their wine means more fun with fewer headaches. Dry Farm Wines only ships wines that meet very stringent criteria: practically sugar free (less than 0.15g per glass), lower alcohol (less than 12.5% alcohol), additive free (there are more than 70 FDA-approved wine-making additives), lower sulfites, organic, and produced by small family farms.All Dry Farm Wines are laboratory tested for purity standards by a certified, independent enologist, and all of their wines are also backed by a 100% Happiness Promise—they will either replace or refund any wine you do not love. Last but not least, I find delicious wines I never would have found otherwise. It’s a lot of fun. Dry Farm Wines has a special offer just for listeners of the podcast—an extra bottle in your first box for just one extra penny. Check out all the details at DryFarmWines.com/Tim.*This episode is also brought to you by Oura! Oura is the company behind the smart ring that delivers personalized sleep and health insights to help you optimize just about everything. I’ve been using it religiously for at least six months, and I was introduced to it by Dr. Peter Attia. It is the only wearable that I wear on a daily basis.With advanced sensors, Oura packs state-of-the-art heart rate, heart-rate variability, temperature, activity, and sleep monitoring technology into a convenient, non-invasive ring. It weighs less than 6 grams and focuses on three key insights—sleep, readiness, and activity.Try it for yourself. The Oura Ring comes in two styles and three colors: Silver, Black, and Matte Black. For $299, you can give or get the gift of health by visiting OuraRing.com.*This episode is also brought to you by LMNT! What is LMNT? It’s a delicious, sugar-free electrolyte drink-mix. I’ve stocked up on boxes and boxes of this and usually use it 1–2 times per day. LMNT is formulated to help anyone with their electrolyte needs and perfectly suited to folks following a keto, low-carb, or Paleo diet. If you are on a low-carb diet or fasting, electrolytes play a key role in relieving hunger, cramps, headaches, tiredness, and dizziness.LMNT came up with a very special offer for you, my dear listeners. They’ve created Tim’s Club: Simply go to DrinkLMNT.com/Tim and select “Subscribe & Save” on any 30-count box of LMNT for only $36. This will be valid for the lifetime of the subscription and you can pause it anytime. And perfect for the warm days, they have a new flavor, Watermelon Salt, which I've been quite enjoying.*If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to convince hard-to-get guests. I also love reading the reviews!For show notes and past guests, please visit tim.blog/podcast.Sign up for Tim’s email newsletter (“5-Bullet Friday”) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim’s books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissFacebook: facebook.com/timferriss YouTube: youtube.com/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, and many more. 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Learn about Aura's state-of-the-art technology that packs heart rate, HRV, temperature activity and sleep monitoring into a convenient ring, and Element's electrolyte formula that is perfect for those following a keto, low carb or paleo diet.
In 1987, a US law was established which allowed the prosecution of substances defined as an analog of a schedule one controlled substance. This marked a pivotal moment in drug policy, and the eclectic career of the man behind it, J. Thomas Ungerleider.
Researcher and psychiatrist Dr. Will Siu discusses the importance of donors using their names and being proud of their involvement in supporting the psychedelic and consciousness research center at Johns Hopkins, in order to combat the unearned stigma surrounding the field. He also addresses the perception that personal experience with psychoactive drugs biases one's research.
The benefits of low doses of drugs such as ayahuasca as opposed to high doses can be significant. However, there are concerns about the danger of using psychedelics in uncontrolled or improperly supervised settings, including documented fatalities.
This podcast discusses the potential benefits and drawbacks of psychedelic therapy with psilocybin, and the importance of ensuring experienced professionals conduct trials over the long-term to assess any potential negative side effects.
The use of iboga or ibogaine for addiction treatment involves not only the pharmacological effects on the alpha-3 beta-4 nicotinic acetylcholine receptor but also the ritual and cultural elements of the Bwiti religion. Traditional practices have been impacted by cultural shifts such as the introduction of opioids in Cameroon and Gabon.
Many communities in Africa are just beginning to recognize the power of their own traditional medicine, specifically Ibogaine, to treat addiction. Synthetic derivatives of Ibogaine like 18MC have slightly different pharmacologies with the same anti-addictive effect.
This podcast episode discusses the sustainability of using plant and animal-derived psychedelics versus synthetically produced ones, urging individuals to consider the ecological damage that may be caused by using non-synthetic options. It also provides advice on how to minimize waste and dispose of it in a sustainable manner when synthesizing any compounds.
In this podcast, the speaker talks about the benefits of involving more people in chemistry, which can reduce problematic relationships with drugs by allowing them to make their own drugs and grow their own plants, knowing everything that goes into producing them.
In this podcast, Hamilton Morris and Tim Ferriss discuss the inaccuracies surrounding the use of toad venom as a psychoactive drug among indigenous and historical communities.
Xenon has been in the spotlight for its potential use as a performance-enhancing drug in the Olympics due to its ability to work as an oxygen deprivation type intervention. It also sources fascination for its place on the periodic table, being just below krypton and having unique properties.
Xenon therapy is being offered in a variety of clinics around the world to treat a range of conditions, despite little evidence to support its efficacy or safety. The gas is also being used recreationally, as inhaling it can change the sound of one's voice.
A producer visits a breatharian clinic for an investigative report and finds the producer and the proprietor of the clinic unconscious due to the irresponsible use of xenon, which led to them vomiting while wearing a gas mask quadruple strapped to their face.
Traditional medicine and rituals are not static and can evolve to address modern problems. It is important to develop rituals that ensure people are getting the best and the most out of them.
The host talks about the lack of scientific books on the topic of 5-Ameo DMT and recommends some books, which are said to be a little bit more in the new age vein, and talks about how the psychedelic industry is growing.
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