Episode

#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
listen on Spotify
1:16:07
Published: Mon Apr 22 2019
Description

David Sinclair is a Professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul Glenn Centre for the Biological Mechanisms of Ageing. Today we hear from a scientist at the cutting edge of longevity research as Professor Sinclair gives us a fascinating insight into the world of anti-ageing. Expect to learn how and why we age, why stabilising the epigenetic landscape may enable a human to live for 1000 years, exactly what tactics Professor Sinclair is using himself to try and extend his life and how fasting, Sirtuins and NAD can be used to promote health and reduce diseases. Extra Stuff: David’s New Book - http://lifespanbook.com/ Follow David on Twitter - https://twitter.com/davidasinclair Inside Tracker - https://www.insidetracker.com Check out everything I recommend from books to products and help support the podcast at no extra cost to you by shopping through this link - https://www.amazon.co.uk/shop/modernwisdom - Get in touch. Join the discussion with me and other like minded listeners in the episode comments on the MW YouTube Channel or message me... Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/ModernWisdomPodcast Email: https://www.chriswillx.com/contact

Chapters
This podcast talks about the process of aging, how our cells and genes deteriorate over time, and different methods available to slow, stop, or reverse the aging process.
00:00 - 02:29 (02:29)
listen on Spotify
Aging
Summary

This podcast talks about the process of aging, how our cells and genes deteriorate over time, and different methods available to slow, stop, or reverse the aging process. Behind-the-scenes footage of David's lab and Harvard Medical School is also available on their YouTube channel.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
Scientists have discovered a combination of resetting genes that could reverse the age of cells in the lab and animals, with hopes for future human clinical trials.
02:29 - 11:21 (08:51)
listen on Spotify
Aging
Summary

Scientists have discovered a combination of resetting genes that could reverse the age of cells in the lab and animals, with hopes for future human clinical trials. The aim is to develop a drug that can slow down the progression of all age-related diseases with a single pill.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
As cells age, proteins that were once laid down in the right place to turn the cell genes on at the right time, become scattered all over the cell, causing it to lose its identity and resemblance to other cells in the body.
11:22 - 15:59 (04:37)
listen on Spotify
Cell Aging
Summary

As cells age, proteins that were once laid down in the right place to turn the cell genes on at the right time, become scattered all over the cell, causing it to lose its identity and resemblance to other cells in the body.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
A scientist expresses gratitude for science communicators who enable the public to learn beyond what traditional news sources provide, especially among younger audiences.
15:59 - 23:26 (07:27)
listen on Spotify
Science communication
Summary

A scientist expresses gratitude for science communicators who enable the public to learn beyond what traditional news sources provide, especially among younger audiences.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
In the future, it may be possible to engineer children to possess certain traits such as high disease resistance and increased intelligence.
23:26 - 31:55 (08:28)
listen on Spotify
genetic engineering
Summary

In the future, it may be possible to engineer children to possess certain traits such as high disease resistance and increased intelligence. However, concerns over the ethical implications of this technology remain.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
It's not just what you eat, but when you eat and how much you eat that is important.
31:55 - 37:29 (05:34)
listen on Spotify
Nutrition
Summary

It's not just what you eat, but when you eat and how much you eat that is important. Different types of intermittent fasting patterns can be followed for weight loss but what you eat is also important.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
Fasting and calorie-restricting can boost the levels of NAD in the cell, which activates repair genes and protectors of the genome called Sirtuins, giving longevity to the yeast cell.
37:29 - 42:45 (05:16)
listen on Spotify
longevity
Summary

Fasting and calorie-restricting can boost the levels of NAD in the cell, which activates repair genes and protectors of the genome called Sirtuins, giving longevity to the yeast cell.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
The episode discusses the use of human growth hormone for anti-aging purposes and the effects of replenishing testosterone levels for young people.
42:45 - 49:41 (06:55)
listen on Spotify
Anti-aging
Summary

The episode discusses the use of human growth hormone for anti-aging purposes and the effects of replenishing testosterone levels for young people.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
High-intensity interval training can stimulate the body's defense networks and increase longevity, more than other forms of exercise such as steady long runs.
49:41 - 53:53 (04:12)
listen on Spotify
Exercise
Summary

High-intensity interval training can stimulate the body's defense networks and increase longevity, more than other forms of exercise such as steady long runs. The concept of hormesis applies, meaning that whatever doesn't kill you makes you stronger.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
The speaker shares that they add powder to their yogurt but are not sure if it's actually yogurt.
53:53 - 56:00 (02:07)
listen on Spotify
Fasting
Summary

The speaker shares that they add powder to their yogurt but are not sure if it's actually yogurt. They also discuss being asked if this breaks their fast.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
A question arose on when people should start thinking about longevity, given that we start calorie restriction and interference with animal pathways after their development, not before.
56:00 - 1:03:27 (07:26)
listen on Spotify
Longevity
Summary

A question arose on when people should start thinking about longevity, given that we start calorie restriction and interference with animal pathways after their development, not before. Some people start consuming supplements early to enhance longevity.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
Increasing people's productivity by solving their health issues can save trillions of dollars every year for the next 10 years, according to statistics by the World Health Organization and Bill Gates.
1:03:27 - 1:08:25 (04:58)
listen on Spotify
Health Issues
Summary

Increasing people's productivity by solving their health issues can save trillions of dollars every year for the next 10 years, according to statistics by the World Health Organization and Bill Gates. This money could be used to solve other significant problems such as environmental issues, species preservation, and preventing global warming.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
This podcast episode discusses how partial reprogramming through resetting the use of antibiotics can rejuvenate cells and help restore youthful information in the body, leading to a longer and healthier life.
1:08:25 - 1:12:59 (04:33)
listen on Spotify
Life extension
Summary

This podcast episode discusses how partial reprogramming through resetting the use of antibiotics can rejuvenate cells and help restore youthful information in the body, leading to a longer and healthier life.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom
The speaker suggests checking out their tweets for new discoveries and recommendations on books, blogs, and online resources for further learning.
1:13:00 - 1:15:53 (02:53)
listen on Spotify
Learning
Summary

The speaker suggests checking out their tweets for new discoveries and recommendations on books, blogs, and online resources for further learning.

Episode
#066 - Professor David Sinclair - Can Humans Live For 1000 Years?
Podcast
Modern Wisdom