Episode
#202 – Rick Doblin: Psychedelics
2:42:17
Published: Wed Jul 21 2021
Description
Rick Doblin is a psychedelics researcher and the founder and executive director of the Multidisciplinary Association for Psychedelic Studies (MAPS). Please support this podcast by checking out our sponsors: - Theragun: https://therabody.com/lex to get 30 day trial - ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free - Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium - Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get special savings EPISODE LINKS: Rick's Twitter: https://twitter.com/RickDoblin MAPS: https://maps.org PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (07:54) - Introduction to psychedelics (11:09) - Psychedelics reveals the inner depths of humans (23:43) - Differences between psychedelics (31:08) - The future of psychedelics (39:52) - Epigenetics (45:49) - DMT (53:16) - Ego dissolution (56:33) - One Flew Over The Cuckoo's Nest (59:32) - Psychedelics and Creativity (1:03:25) - MKUltra and the Grateful Dead (1:08:04) - Ted Kaczynski (1:13:46) - Timothy Leary (1:21:10) - Good Friday Experiment (1:25:46) - Forming of MAPS (1:37:01) - Gaining access to psychedelics (1:45:30) - MDMA Medical Trials (2:17:00) - Clinical Trials for other substances (2:21:43) - Future of society with psychedelics (2:26:13) - Big Pharma (2:32:32) - Advice for the younger generations (2:38:17) - Meaning of life
Chapters
Rick Doblin discusses the potential benefits of using psychedelics for exploring the mind and how scientific research into their safety and efficacy can help establish proper usage protocols.
00:00 - 01:45 (01:45)
Summary
Rick Doblin discusses the potential benefits of using psychedelics for exploring the mind and how scientific research into their safety and efficacy can help establish proper usage protocols.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
The speaker discusses their preferred resources for productivity and wellness, including Blinkist and a cooling blanket.
01:45 - 08:02 (06:16)
Summary
The speaker discusses their preferred resources for productivity and wellness, including Blinkist and a cooling blanket.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
This podcast discusses how the mind focuses on fulfilling our core needs, and how natural substances like classic psychedelics and MDMA can catalyze natural states of mind, often ignored or pushed away, providing both positive and negative experiences.
08:02 - 17:57 (09:55)
Summary
This podcast discusses how the mind focuses on fulfilling our core needs, and how natural substances like classic psychedelics and MDMA can catalyze natural states of mind, often ignored or pushed away, providing both positive and negative experiences.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
Researchers are looking into the effects of DMT on people and whether it can provide insight into the physics of consciousness or reveal the connection between us and other living life forms, though our cognitive capabilities may be limited to fully understand it.
17:57 - 28:00 (10:02)
Summary
Researchers are looking into the effects of DMT on people and whether it can provide insight into the physics of consciousness or reveal the connection between us and other living life forms, though our cognitive capabilities may be limited to fully understand it.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
This episode dives into the default mode network in our brains, the potential of personalized chemotherapy, the use of psychedelics in ancient ceremonies, and the possibilities of engineering new psychedelics and where they may take our minds.
28:00 - 45:16 (17:16)
Summary
This episode dives into the default mode network in our brains, the potential of personalized chemotherapy, the use of psychedelics in ancient ceremonies, and the possibilities of engineering new psychedelics and where they may take our minds.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
The speaker describes their experience smoking DMT for the first time and feeling a sense of safety and vulnerability within a group of trusted friends.
45:18 - 51:53 (06:34)
Summary
The speaker describes their experience smoking DMT for the first time and feeling a sense of safety and vulnerability within a group of trusted friends. They also reflect on the idea that our innermost sense of self is shaped by millions of people throughout history.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
Psychedelics can help individuals find their calling, vision, and unique leverage point while exploring mental states in depth.
51:53 - 1:05:06 (13:12)
Summary
Psychedelics can help individuals find their calling, vision, and unique leverage point while exploring mental states in depth. Starting with trauma, it could empower individuals' creativity for lifelong exploration with more effective and scientific approaches.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
The CIA's MKUltra program involved giving LSD to individuals in an attempt to control their internal experiences and prevent political involvement.
1:05:06 - 1:14:52 (09:45)
Summary
The CIA's MKUltra program involved giving LSD to individuals in an attempt to control their internal experiences and prevent political involvement. While psychedelics have the potential for healing, the unethical methods used in the MKUltra program violated human rights.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
Dr. James Fadiman discusses the Good Friday experiment and his studies on psychedelics in religious settings leading to mystical experiences.
1:14:52 - 1:24:13 (09:21)
Summary
Dr. James Fadiman discusses the Good Friday experiment and his studies on psychedelics in religious settings leading to mystical experiences. As psychedelics become increasingly mainstream, we learn about their cultural impact on creativity and overall behavior.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
In this podcast episode, the founder of MAPS (Multidisciplinary Association for Psychedelic Studies) discusses the history of MDMA and how it led to the creation of MAPS as a nonprofit pharmaceutical company to change attitudes towards therapeutic drug use in America.
1:24:13 - 1:30:34 (06:20)
Summary
In this podcast episode, the founder of MAPS (Multidisciplinary Association for Psychedelic Studies) discusses the history of MDMA and how it led to the creation of MAPS as a nonprofit pharmaceutical company to change attitudes towards therapeutic drug use in America.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
Rick Doblin shares how a government bill signed during Reagan's administration provided incentives for developing drugs that were off patent, and how this helped fund medical breakthroughs.
1:30:35 - 1:36:54 (06:19)
Summary
Rick Doblin shares how a government bill signed during Reagan's administration provided incentives for developing drugs that were off patent, and how this helped fund medical breakthroughs. The incentives, called data exclusivity, protect research data for a period of time, allowing companies to market their medicine without competition.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
Despite the potential for therapeutic benefits, progress towards the legalization of psychedelic drugs has been slow.
1:36:54 - 1:45:24 (08:30)
Summary
Despite the potential for therapeutic benefits, progress towards the legalization of psychedelic drugs has been slow. However, there have been recent developments with the passing of drug decriminalization in Oregon and compassionate access to psilocybin in Canada.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
Research with classic psychedelics such as LSD and psilocybin has demonstrated a link between the depth of the mystical experience and therapeutic outcomes for addiction, OCD, and life-threatening illnesses.
1:45:24 - 1:59:00 (13:35)
Summary
Research with classic psychedelics such as LSD and psilocybin has demonstrated a link between the depth of the mystical experience and therapeutic outcomes for addiction, OCD, and life-threatening illnesses. Phase three studies with MDMA have also shown therapeutic benefits, but inactive placebos may be even more effective than low doses of MDMA.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
The statistical analysis of clinical trials involves calculating the effect size of different treatments and determining the sample size needed for the study.
1:59:00 - 2:08:51 (09:51)
Summary
The statistical analysis of clinical trials involves calculating the effect size of different treatments and determining the sample size needed for the study. The placebo subtracted effect size is used to measure the effect of the treatment, while sample size re-estimation is done in phase three trials to account for any variations in the results.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
While conducting clinical trials on the use of MDMA-assisted therapy for treating PTSD, researchers found that the rate of suicide and suicide attempts was very low compared to the general population.
2:08:51 - 2:15:17 (06:25)
Summary
While conducting clinical trials on the use of MDMA-assisted therapy for treating PTSD, researchers found that the rate of suicide and suicide attempts was very low compared to the general population.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
The use of psychedelics in therapy is giving hope to the practice of psychiatry and psychotherapy by offering different approaches and treatments for conditions that have left people suffering.
2:15:17 - 2:26:48 (11:31)
Summary
The use of psychedelics in therapy is giving hope to the practice of psychiatry and psychotherapy by offering different approaches and treatments for conditions that have left people suffering. The responsible use of psychedelics, drug policy reform and honest drug education are vital for this field's advancement.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
The debate on whether big pharma should optimize for profit or benefit when treating mental health is ongoing.
2:26:48 - 2:36:46 (09:57)
Summary
The debate on whether big pharma should optimize for profit or benefit when treating mental health is ongoing. However, ultimately, therapists and doctors who care more about the patients should be given more power than profit-maximizing companies.
Episode#202 – Rick Doblin: Psychedelics
PodcastLex Fridman Podcast
The idea that death makes life precious is discussed, as the hosts reflect on how the idea applies in their own lives.
2:36:46 - 2:42:09 (05:23)
Summary
The idea that death makes life precious is discussed, as the hosts reflect on how the idea applies in their own lives.