Chapter
Systems Medicine for Personalized Healthcare
2:23:31 - 2:38:02 (14:30)
The field of medicine is moving towards personalized treatment based on a patient's genetic markers and perturbations. Collaborations are ongoing to look at multi-tissue perturbations across the body in the context of exercise and nutritional interventions, leading to the delivery of specific drugs and interventions into specific cell types for the prevention and treatment of diseases such as Alzheimer's.
Clips
The study of Alzheimer's has progressed to the cell level, where predictive models can be used to identify how the unique genome of each cell related to cognition and pathology.
2:23:31 - 2:30:06 (06:34)
Summary
The study of Alzheimer's has progressed to the cell level, where predictive models can be used to identify how the unique genome of each cell related to cognition and pathology. A collaboration with the Goodyear lab is also examining multi-tissue perturbations in the context of exercise and nutrition to understand how cell-to-cell communications are changing across them.
ChapterSystems Medicine for Personalized Healthcare
Episode#133 – Manolis Kellis: Biology of Disease
PodcastLex Fridman Podcast
Our uniquely human ability to consume energy-rich food has allowed us to develop a large and efficient brain, but it also causes oxidative damage that contributes to diseases like Alzheimer's.
2:30:06 - 2:31:35 (01:29)
Summary
Our uniquely human ability to consume energy-rich food has allowed us to develop a large and efficient brain, but it also causes oxidative damage that contributes to diseases like Alzheimer's. Understanding the impact of energetics on the brain requires consideration of multiple systems, including the immune and metabolic systems.
ChapterSystems Medicine for Personalized Healthcare
Episode#133 – Manolis Kellis: Biology of Disease
PodcastLex Fridman Podcast
As we push F-zine into new ages, new health challenges arise such as cancer, Alzheimer's and other brain related disorders, metabolic disorders, and regeneration.
2:31:35 - 2:34:50 (03:15)
Summary
As we push F-zine into new ages, new health challenges arise such as cancer, Alzheimer's and other brain related disorders, metabolic disorders, and regeneration. The human immune system has been shaped by selective events in history and continues to cope with the density of life.
ChapterSystems Medicine for Personalized Healthcare
Episode#133 – Manolis Kellis: Biology of Disease
PodcastLex Fridman Podcast
With the development of personalized medicine, medical intervention can now be based on a patient's specific set of genetic markers and perturbations.
2:34:50 - 2:38:02 (03:11)
Summary
With the development of personalized medicine, medical intervention can now be based on a patient's specific set of genetic markers and perturbations. This allows for precise interventions and drug delivery, as well as the ability to move from a disease state to a physiologically improved state.