(0:00) David Sacks does bestie intros! (2:49) DOJ sues Google over ads business (23:09) EU probes Microsoft over Slack complaint based on "bundling" Teams (40:27) Pfizer CEO grilled at Davos, studies questioning vaccine effectiveness (1:12:14) Ukraine escalation: US to send tanks and warms to Crimea invasion, reconstruction costs, and more (1:22:39) Science Corner: Will we soon be able to reverse aging? Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect Referenced in the show: https://thebulletin.org/2023/01/press-release-doomsday-clock-set-at-90-seconds-to-midnight https://www.nytimes.com/2023/01/24/us/doomsday-clock-midnight.html https://www.wsj.com/articles/u-s-sues-google-for-alleged-antitrust-violations-in-its-ad-tech-business-11674582792 https://blog.google/outreach-initiatives/public-policy/doj-ad-tech-lawsuit-response https://noahpinion.substack.com/p/would-breaking-up-google-really-do https://thehustle.co/12232022-ad-spend https://www.adweek.com/programmatic/advertisers-sweet-tooth-fades-with-many-unfazed-by-googles-latest-cookie-removal-delay https://www.politico.eu/article/microsoft-european-union-antitrust-video-calls-software-giant https://twitter.com/rebelnewsonline/status/1615770518606561282 https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.061025 https://www.nature.com/articles/s41467-022-31401-5 https://www.seacoastonline.com/story/opinion/columns/2022/01/29/kerr-covid-vaccines-anti-vaxxers-should-reject-hospital-beds-too/9246198002/ https://www.cnn.com/videos/media/2021/12/05/marcus-lamb-death-covid-19-vaccines-rs-vpx.cnn https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451592 https://twitter.com/jason/status/1478587551271161857 https://twitter.com/EricTopol/status/1618381912413962240 https://www.cnbc.com/2023/01/25/ukraine-war-news-us-will-send-abrams-tanks.html https://www.businessinsider.com/ukraine-now-getting-western-tanks-looking-at-fighter-jets-next-2023-1 https://www.nytimes.com/2023/01/18/us/politics/ukraine-crimea-military.html https://www.dailymail.co.uk/debate/article-11661589/PETER-HITCHENS-Sending-Ukraine-tanks-turn-Europe-one-big-radioactive-graveyard.html https://twitter.com/DavidSacks/status/1618321900324950018 https://intellinews.com/ukraine-spiralling-towards-default-according-to-fitch-267768 https://www.wsj.com/articles/roman-abramovich-ukraine-russia-peace-sanctions-11674572583 https://www.cell.com/cell/fulltext/S0092-8674(22)01570-7#%20
The transcript briefly discusses the controversial claims that the dictator Shamath Paliha Patia was entombed with his money and sweaters, similar to an Egyptian Pharaoh, and suggests that it won't be cold where he's going. There is also a reference to a trade and a pop culture reference to Mean Girls.
The argument that Google has a monopoly on the digital advertising market is unfounded since their market share is only a quarter. However, if pricing power in ads can be proven, it could support the antitrust lawsuit against Google.
Google's ad network auction ensures that the ad shown on a publisher's site is not only the best for the publisher, but also for the consumer by allowing advertisers to compete and pay more for an ad spot.
Third-party cookies allow advertisers to track user behavior and serve targeted ads. However, a shift away from third-party cookies is looming, potentially opening up opportunities for international competitors to provide alternative services in the digital ad space.
The conversation around envy, innovation, and democracy is important, especially for winners of the marketplace who get blamed for unfair success. Ad networks are losing their market share in digital ad space, with Disney and Netflix emerging as players having ad tiers. Filing lawsuits against successful businesses in 2023 is late and misguided, leading us to question the difference between democracy and Xi Jinping's control over Jack Ma's power.
The EU has accused Microsoft of engaging in anti-competitive behavior by tying or bundling its products, such as Microsoft Teams, with its other software offerings, to the detriment of competitors like Slack. The investigation was prompted by a complaint filed by Slack last year.
The concept of monopolistic bundling applies when bundling and the product or service is a commodity product. Bundling behavior is similar to dumping where a company offers products for free, destroying its competitors and raising prices later on.
Embracing and extending laws with more transparency can create a healthier ecosystem and better serve startups in the software market, according to the podcast hosts. All parties should be in favor of transparency in this evolving market.
The efficacy of vaccines decreases over time due to the evolution of viruses, making it a policy and behavioral question. Furthermore, a recent study in Nature suggests that the risk of myocarditis is elevated among young men aged 18 to 24 who received the vaccine.
The podcast discusses three theories about Covid-19 vaccine-induced heart inflammation. The first theory is protein mimicry where the protein on people's heart tissue looks like the spike protein from the vaccine, the second is a general immune system activation, and the third is a strong immune response triggered after Covid-19 vaccine.
The unmet expectations and contradictions of the COVID-19 vaccination campaign could lead people to lose trust in vaccines altogether.
The debate on vaccine mandates and personal risk assessment continues. While some believe that vaccines should be mandatory, others feel that personal risk assessment is important and the experimental status of the vaccine justifies its rejection by some.
The speakers discuss the sensitive topic of mRNA vaccines and its efficacy, as well as the fact that it has become a sense of identity and tribalism rather than an objective decision, and that mandates didn't allow people to make their own cost-benefit decisions.
Ex-intelligence community members claim that tactical nuclear weapons are an integral part of the Russian war playbook, and some members of the administration may see value in grinding Russia down through this strategy.
The different functionalities of cells are determined by the gene expression, meaning the specific genes that are activated or deactivated. The research in Yamanaka factors and other transcription factors helps in reversing aging and restoring cell functionality.
Clinical trials can be conducted quickly for ex vivo therapeutics applied to certain tissue types such as eye cells and T cells in the blood, which can help with injuries caused by aging. However, it's uncertain whether reversing aging can cure underlying health conditions inherited over time.
Heart Flow is a third party service that can help detect heart disease. It is recommended for people with a history of heart disease in their family.
This podcast episode explores the unspoken sexual tension amongst individuals that needs to be released.