Episode

904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
Description
Aging is a disease.Everyone gets old. But did you ever think of the symptoms of aging as a disease that can be cured?I'd heard about Dr. David Sinclair and his ground-breaking longevity research, and I knew he would be a fascinating person to interview about this idea.We ended up going really deep into the science of why we age, how to reverse it, and what is actually in our control.David told stories he'd never shared before, and I kept asking questions because I was so interested in what he was telling me.David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School. He is an inventor on 35 patents and has received more than 35 awards and honors. In 2014, he was on Time Magazine’s list of the “100 Most Influential People in the World,” and listed as Time's Top 50 in healthcare in 2018.In this conversation, we discussed all of my top questions on why we age, how much of it is reversible, and all of the ways I've heard to increase your longevity and health.David is a wealth of wisdom on all these topics, and he also shared some of the hardest times of his life, including watching his mother die of lung cancer and why that impacted his work so much.If you are committed to improving your health and living a long and healthy life, this conversation is a must-listen in Episode 904.Is it possible to reverse death? (7:42)What are the main ways to turn on the longevity genes? (9:30)How do you say no to all the food offers around you? (17:30)How did you get fascinated by longevity and anti-aging? (19:15)How did you recover from a major career setback? (37:06)What was the biggest lesson you learned from a year of being homeless? (49:28)How important are heat and cold therapy to anti-aging? (59:38)What is the ideal way to use fasting to improve your health? (1:05:42)How old do you think you’ll be able to live? (1:14:15)How much does inflammation play into the longevity of your life? (1:20:44)How our body’s built-in defenses against aging work (1:12)Why 3 meals a day is too much food for most people (10:09)The main benefits of a plant-based diet for longevity (13:13)Why it’s important to remember that there will always be another meal (15:10)Why death is so shocking to us even though it happens all the time (21:01)The molecule that has been proven to protect against a variety of diseases (29:34)The story that David has never told of how he was homeless after college (44:45)How cells lose their ability to stay young (55:32)Lewis’ experience doing a cold-exposure intensive in Poland with Wim Hof (1:08:45)Plus much more...If you enjoyed this episode, check out the video, show notes and more at http://www.lewishowes.com/904 and follow at instagram.com/lewishowes
Chapters
Dr. David Sinclair, a professor at Harvard Medical School, shares his research on how to reverse aging through extreme cold, fasting, and biohacking.
00:00 - 04:48 (04:48)
Summary
Dr. David Sinclair, a professor at Harvard Medical School, shares his research on how to reverse aging through extreme cold, fasting, and biohacking. He also talks about the importance of staying true to your beliefs and offers tips on how to improve your health.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
Aging has several hallmarks, including the shortening of telomeres and the decline of battery-packed mitochondria, among others.
04:48 - 14:05 (09:17)
Summary
Aging has several hallmarks, including the shortening of telomeres and the decline of battery-packed mitochondria, among others. However, scientists believe that lifestyle factors such as community, diet, and sleep can account for 80% of an individual's health in old age.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
By activating our longevity genes, diet and exercise can help us live healthier, longer lives according to experts.
14:05 - 22:36 (08:30)
Summary
By activating our longevity genes, diet and exercise can help us live healthier, longer lives according to experts. Getting into the mindset of being willing to go hungry and embracing a combination of healthy habits is key.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
The speaker shares how he went from being a big dumb jock to embracing the enjoyment of life in the present moment, instead of worrying about the future breakthroughs that will extend human lifespan for generations to come.
22:36 - 32:48 (10:12)
Summary
The speaker shares how he went from being a big dumb jock to embracing the enjoyment of life in the present moment, instead of worrying about the future breakthroughs that will extend human lifespan for generations to come.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
The hosts discuss the connection between long life and fatty acids, found in foods such as olive oil and red wine, that mimic the effects of rose virtual in generating free fatty acids in the body.
32:48 - 43:51 (11:02)
Summary
The hosts discuss the connection between long life and fatty acids, found in foods such as olive oil and red wine, that mimic the effects of rose virtual in generating free fatty acids in the body.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
The speaker shares his experiences of traveling with little money and how he ended up attending a LinkedIn event after meeting someone at a conference; he also talks about his childhood dream of becoming an all-American athlete.
43:51 - 52:50 (08:58)
Summary
The speaker shares his experiences of traveling with little money and how he ended up attending a LinkedIn event after meeting someone at a conference; he also talks about his childhood dream of becoming an all-American athlete.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
The epigenome plays a crucial role in determining which genes are expressed in our cells.
52:50 - 1:02:04 (09:14)
Summary
The epigenome plays a crucial role in determining which genes are expressed in our cells. Dr. David Sinclair discusses the connection between the epigenome, aging, and disease.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
Brown fat, full of energy and heat producing mitochondria, is metabolically active and helps burn energy by generating heat through exposure to cold temperatures.
1:02:04 - 1:09:55 (07:50)
Summary
Brown fat, full of energy and heat producing mitochondria, is metabolically active and helps burn energy by generating heat through exposure to cold temperatures. Daily cold showers or ice plunges can help generate brown fat, which helps with energy burn and heat production.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
Brendan Schaub talks about his experience with Wim Hof and the importance of group endurance and supervision when pushing oneself to physical limits.
1:09:56 - 1:18:08 (08:12)
Summary
Brendan Schaub talks about his experience with Wim Hof and the importance of group endurance and supervision when pushing oneself to physical limits.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
Dr. David Sinclair talks about life extension research and his recent book which aims to help people live longer and healthier lives.
1:18:08 - 1:26:27 (08:19)
Summary
Dr. David Sinclair talks about life extension research and his recent book which aims to help people live longer and healthier lives. He shares his optimism on his research and has discovered a reset switch in cells that can help reset the age of individuals.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
David Sinclair, author of Lifespan, expresses his appreciation for those who have dedicated their lives to helping others and shares his new definition of greatness, which includes those who choose to do non-profit work and raise a family.
1:26:27 - 1:32:39 (06:12)
Summary
David Sinclair, author of Lifespan, expresses his appreciation for those who have dedicated their lives to helping others and shares his new definition of greatness, which includes those who choose to do non-profit work and raise a family.
Episode904 Live a Longer Life and Reverse Aging with Dr. David Sinclair
PodcastThe School of Greatness
This podcast aims to provide valuable insights and tools to help listeners maximize their potential and improve their lives.
1:32:39 - 1:35:17 (02:37)
Summary
This podcast aims to provide valuable insights and tools to help listeners maximize their potential and improve their lives. Dr. David Sinclair's book is recommended as a resource for achieving this goal.