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LDL cholesterol below 30 or an APO-B below 40 mg/dL for a long time means the risk of suffering ASCVD is low.
56:12 - 1:00:02 (03:50)
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APO-B
Summary

LDL cholesterol below 30 or an APO-B below 40 mg/dL for a long time means the risk of suffering ASCVD is low. By late 30s or early 40s, APO-B should be lowered to below the 20th percentile, especially for patients with significant genetic abnormalities like familial hypercholesterolemia.

Chapter
Evidence-Based Optimal Levels of APOB for Cardiovascular Health
Episode
#599: New Insights from Sam Harris, Dr. Peter Attia, Ramit Sethi, and Elizabeth Gilbert
Podcast
The Tim Ferriss Show
In a study on the effects of metformin supplementation on the lifespan of Fisher 344 rats, no significant lifespan extension was observed.
52:27 - 54:31 (02:04)
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Metformin
Summary

In a study on the effects of metformin supplementation on the lifespan of Fisher 344 rats, no significant lifespan extension was observed. While it's important to standardize dosage, it may be more effective to mix metformin into the animals' food rather than injecting them with it directly.

Chapter
The Pros and Cons of Metformin Use for Diabetes Management
Episode
#188: Dom D'Agostino on Disease Prevention, Cancer, and Living Longer
Podcast
The Tim Ferriss Show
Even if a search engine can generate a list of documents with the right answer, there is still the challenge of determining where the answer is located within those documents.
1:08:32 - 1:10:43 (02:10)
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Search Engines
Summary

Even if a search engine can generate a list of documents with the right answer, there is still the challenge of determining where the answer is located within those documents.

Chapter
The Challenge of Finding Answers in a Sea of Information
Episode
David Ferrucci: IBM Watson, Jeopardy & Deep Conversations with AI
Podcast
Lex Fridman Podcast
The importance of starting to invest at a young age is discussed, referencing a successful businessman who started at 21 years old and saw impressive growth over time through a simple strategy.
27:40 - 29:14 (01:34)
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Investing
Summary

The importance of starting to invest at a young age is discussed, referencing a successful businessman who started at 21 years old and saw impressive growth over time through a simple strategy.

Chapter
Discussing the Valuation of Social Networks
Episode
"Sara's List" Update: 12 Startups Where Stock Grants Will Make You A Millionaire
Podcast
My First Million
The likelihood of having a severe reaction to the SARS coronavirus is higher (10 to 15 times) for people over 65 and those who smoke a pack a day (at least 3500 cigarettes per year).
31:34 - 33:09 (01:34)
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Coronavirus Risk Factors
Summary

The likelihood of having a severe reaction to the SARS coronavirus is higher (10 to 15 times) for people over 65 and those who smoke a pack a day (at least 3500 cigarettes per year). Three potential risk factors for coronavirus have been identified.

Chapter
The Severity of COVID-19 and its Impact on Specific Demographics
Episode
E0: COVID-19 Political, Economic & Social Ramifications featuring The Production Board's David Friedberg (frmly Founder/CEO, The Climate Corporation)
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
In 1979, famous logo designer Saul Bass created an updated trefoil version of the original Girl Scout cookie logo, which has remained the basis of the design to this day.
38:24 - 41:10 (02:46)
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Girl Scout Cookies
Summary

In 1979, famous logo designer Saul Bass created an updated trefoil version of the original Girl Scout cookie logo, which has remained the basis of the design to this day.

Chapter
The Tale of Samoas, or Caramel Delights
Episode
Girl Scouts: More than cookie sellers
Podcast
Stuff You Should Know
Learn how to check the temperature, appearance, texture, and smell of your compost to determine if it's done and ready to use as soil amendment.
51:16 - 52:31 (01:14)
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composting
Summary

Learn how to check the temperature, appearance, texture, and smell of your compost to determine if it's done and ready to use as soil amendment. A diverse microbial population and an earthy smell are good indicators that the composting process is complete.

Chapter
Benefits of Letting Compost Cure
Episode
Selects: Composting: Nature's Most Interesting Process
Podcast
Stuff You Should Know
Learn about Horvath clocks, a method developed by David Sinclair and others, that tap into the epigenome and genome to give insight into our biological age.
1:32:52 - 1:36:21 (03:29)
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Horvath Clocks
Summary

Learn about Horvath clocks, a method developed by David Sinclair and others, that tap into the epigenome and genome to give insight into our biological age. By measuring and averaging ear circumference and subtracting 88.1, Horvath clocks can calculate your biological age.

Chapter
Ginkgo Biloba and Its Limited Effect on Tinnitus
Episode
The Science of Hearing, Balance & Accelerated Learning
Podcast
Huberman Lab
A formula exists that can measure biological age based on ear size.
1:31:20 - 1:32:52 (01:31)
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Biological Age
Summary

A formula exists that can measure biological age based on ear size. By taking the circumference of the ears in millimeters and subtracting it from the individual's chronological age, a biological age is calculated.

Chapter
Ginkgo Biloba and Its Limited Effect on Tinnitus
Episode
The Science of Hearing, Balance & Accelerated Learning
Podcast
Huberman Lab
This podcast discusses the hidden inflation of the US dollar, which has been approximately 7% a year for the past century, though this figure is never acknowledged by government or conventional economists.
26:50 - 31:29 (04:38)
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US Dollar
Summary

This podcast discusses the hidden inflation of the US dollar, which has been approximately 7% a year for the past century, though this figure is never acknowledged by government or conventional economists.

Chapter
The Relationship between Money Supply Expansion and Investment Returns
Episode
#276 – Michael Saylor: Bitcoin, Inflation, and the Future of Money
Podcast
Lex Fridman Podcast
The phospholipids found in shellfish, particularly plasmallogen in scallops, can greatly improve the functioning of mitochondrial systems and the brain.
44:25 - 46:27 (02:01)
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Health
Summary

The phospholipids found in shellfish, particularly plasmallogen in scallops, can greatly improve the functioning of mitochondrial systems and the brain.

Chapter
Benefits of Consuming Shellfish for Mitochondrial System and Gut Health
Episode
991 Live Longer and Hack Your Health w/Dr. Steven Gundry
Podcast
The School of Greatness
The speaker raises concern about the justice system and suggests looking into the sentences of other incarcerated individuals.
1:58:35 - 1:59:59 (01:24)
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Justice system
Summary

The speaker raises concern about the justice system and suggests looking into the sentences of other incarcerated individuals. The speaker believes that it is a flawed system when people receive lengthy sentences of 20, 30, or even 40 years.

Chapter
Examining a Potential Legal Defense: Insanity Caused by Prescription Medication
Episode
E109: 2022 Bestie Awards Live from Twitter HQ
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
This podcast discusses the idea of the government replacing all the medians in America with turf instead of grass as a solution to save 20-30% of water allocation to watering lawns.
21:23 - 22:51 (01:28)
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Turfing, Water Conservation
Summary

This podcast discusses the idea of the government replacing all the medians in America with turf instead of grass as a solution to save 20-30% of water allocation to watering lawns.

Chapter
Scrappy Entrepreneurs
Episode
#85 - Why Privacy is Big Business and the Multi-Million Dollar Ideas Hidden in Plain Sight
Podcast
My First Million
This podcast episode discusses the duration of market retracements, comparing the current retracement to the dotcom bubble and the retracement that occurred in 1987.
1:03:22 - 1:05:16 (01:54)
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Market Retracements
Summary

This podcast episode discusses the duration of market retracements, comparing the current retracement to the dotcom bubble and the retracement that occurred in 1987.

Chapter
The Economic Challenges of Tech Companies
Episode
E0: COVID-19 Political, Economic & Social Ramifications featuring The Production Board's David Friedberg (frmly Founder/CEO, The Climate Corporation)
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
Organic chemists have created a giant dictionary of interconnected puzzle pieces to help identify unknown molecules using spectroscopy, called the spectroscopic roadmap.
46:47 - 51:09 (04:21)
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Chemistry
Summary

Organic chemists have created a giant dictionary of interconnected puzzle pieces to help identify unknown molecules using spectroscopy, called the spectroscopic roadmap.

Chapter
Studying Mysterious Molecules
Episode
#195 – Clara Sousa-Silva: Searching for Signs of Life on Venus and Other Planets
Podcast
Lex Fridman Podcast
The United States is experiencing a step prior to job losses, where people's 401ks are being destroyed, and wages are hit hard by inflation and high food and gas prices, while home sales are holding up historically.
26:02 - 30:26 (04:23)
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United States
Summary

The United States is experiencing a step prior to job losses, where people's 401ks are being destroyed, and wages are hit hard by inflation and high food and gas prices, while home sales are holding up historically.

Chapter
The Impact of Inflation and Supply-Side Issues on Average Consumers
Episode
E86: Macro outlook: jobs, housing, inflation + Dutch farmers protests & EU climate missteps
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
The likelihood of a global catastrophic event, such as a pandemic or nuclear war, is higher than most of us would like to believe, with a 20% risk of causing hundreds of millions of deaths.
1:11:36 - 1:13:36 (02:00)
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Catastrophic Event
Summary

The likelihood of a global catastrophic event, such as a pandemic or nuclear war, is higher than most of us would like to believe, with a 20% risk of causing hundreds of millions of deaths.

Chapter
The Slow Pace of Change in Technology
Episode
#512 - Will MacAskill - How Long Could Humanity Continue For?
Podcast
Modern Wisdom
A large portion of differences observed among individuals are due to inherited DNA differences.
08:17 - 11:29 (03:11)
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Inherited DNA Differences
Summary

A large portion of differences observed among individuals are due to inherited DNA differences. Recent DNA technology advancements are allowing for predictions to be made at the individual level based on these differences.

Chapter
Behavioral Genetics and Differences in Inherited DNA
Episode
#353 - Robert Plomin - How Do Genes Influence Our Behaviour?
Podcast
Modern Wisdom
The likelihood of changing fundamental beliefs is discussed, with a range of probabilities from 8% to 20%.
1:18:05 - 1:18:56 (00:50)
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Probability
The speaker discusses managing wealth and the risks involved in investing in individual stocks.
55:06 - 56:42 (01:36)
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Wealth Management