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In a study on the effects of metformin supplementation on the lifespan of Fisher 344 rats, no significant lifespan extension was observed.
52:27 - 54:31 (02:04)
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Metformin
Summary

In a study on the effects of metformin supplementation on the lifespan of Fisher 344 rats, no significant lifespan extension was observed. While it's important to standardize dosage, it may be more effective to mix metformin into the animals' food rather than injecting them with it directly.

Chapter
The Pros and Cons of Metformin Use for Diabetes Management
Episode
#188: Dom D'Agostino on Disease Prevention, Cancer, and Living Longer
Podcast
The Tim Ferriss Show
The likelihood of having a severe reaction to the SARS coronavirus is higher (10 to 15 times) for people over 65 and those who smoke a pack a day (at least 3500 cigarettes per year).
31:34 - 33:09 (01:34)
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Coronavirus Risk Factors
Summary

The likelihood of having a severe reaction to the SARS coronavirus is higher (10 to 15 times) for people over 65 and those who smoke a pack a day (at least 3500 cigarettes per year). Three potential risk factors for coronavirus have been identified.

Chapter
The Severity of COVID-19 and its Impact on Specific Demographics
Episode
E0: COVID-19 Political, Economic & Social Ramifications featuring The Production Board's David Friedberg (frmly Founder/CEO, The Climate Corporation)
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
LDL cholesterol below 30 or an APO-B below 40 mg/dL for a long time means the risk of suffering ASCVD is low.
56:12 - 1:00:02 (03:50)
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APO-B
Summary

LDL cholesterol below 30 or an APO-B below 40 mg/dL for a long time means the risk of suffering ASCVD is low. By late 30s or early 40s, APO-B should be lowered to below the 20th percentile, especially for patients with significant genetic abnormalities like familial hypercholesterolemia.

Chapter
Evidence-Based Optimal Levels of APOB for Cardiovascular Health
Episode
#599: New Insights from Sam Harris, Dr. Peter Attia, Ramit Sethi, and Elizabeth Gilbert
Podcast
The Tim Ferriss Show
In 1979, famous logo designer Saul Bass created an updated trefoil version of the original Girl Scout cookie logo, which has remained the basis of the design to this day.
38:24 - 41:10 (02:46)
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Girl Scout Cookies
Summary

In 1979, famous logo designer Saul Bass created an updated trefoil version of the original Girl Scout cookie logo, which has remained the basis of the design to this day.

Chapter
The Tale of Samoas, or Caramel Delights
Episode
Girl Scouts: More than cookie sellers
Podcast
Stuff You Should Know
The likelihood of a global catastrophic event, such as a pandemic or nuclear war, is higher than most of us would like to believe, with a 20% risk of causing hundreds of millions of deaths.
1:11:36 - 1:13:36 (02:00)
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Catastrophic Event
Summary

The likelihood of a global catastrophic event, such as a pandemic or nuclear war, is higher than most of us would like to believe, with a 20% risk of causing hundreds of millions of deaths.

Chapter
The Slow Pace of Change in Technology
Episode
#512 - Will MacAskill - How Long Could Humanity Continue For?
Podcast
Modern Wisdom
In this episode, the hosts discuss the lab leak hypothesis for the pandemic and the possible origins of Bitcoin.
08:41 - 09:50 (01:09)
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Lab Leak, Bitcoin
Summary

In this episode, the hosts discuss the lab leak hypothesis for the pandemic and the possible origins of Bitcoin. They explore the idea of an individual designing Bitcoin and the likelihood of external influences, such as the NSA, being involved.

Chapter
The Evolution of the Bitcoin Community
Episode
#196 with Dan Held - Who Really Created Bitcoin & Other Crypto Startup Ideas
Podcast
My First Million
Learn how to check the temperature, appearance, texture, and smell of your compost to determine if it's done and ready to use as soil amendment.
51:16 - 52:31 (01:14)
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composting
Summary

Learn how to check the temperature, appearance, texture, and smell of your compost to determine if it's done and ready to use as soil amendment. A diverse microbial population and an earthy smell are good indicators that the composting process is complete.

Chapter
Benefits of Letting Compost Cure
Episode
Selects: Composting: Nature's Most Interesting Process
Podcast
Stuff You Should Know
The United States is experiencing a step prior to job losses, where people's 401ks are being destroyed, and wages are hit hard by inflation and high food and gas prices, while home sales are holding up historically.
26:02 - 30:26 (04:23)
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United States
Summary

The United States is experiencing a step prior to job losses, where people's 401ks are being destroyed, and wages are hit hard by inflation and high food and gas prices, while home sales are holding up historically.

Chapter
The Impact of Inflation and Supply-Side Issues on Average Consumers
Episode
E86: Macro outlook: jobs, housing, inflation + Dutch farmers protests & EU climate missteps
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
Venus flytraps grow in areas that get cold in the winter, so if you're growing one in a terrarium during November to February, take it out and place it in a cold area.
39:32 - 42:34 (03:02)
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Venus Flytraps
Summary

Venus flytraps grow in areas that get cold in the winter, so if you're growing one in a terrarium during November to February, take it out and place it in a cold area. Also, don't trigger the plant's closures for fun as it will only shorten its lifespan.

Chapter
Growing and Caring for Cymbidium Orchids
Episode
Venus Flytraps: Plant or Monster?
Podcast
Stuff You Should Know
The importance of starting to invest at a young age is discussed, referencing a successful businessman who started at 21 years old and saw impressive growth over time through a simple strategy.
27:40 - 29:14 (01:34)
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Investing
Summary

The importance of starting to invest at a young age is discussed, referencing a successful businessman who started at 21 years old and saw impressive growth over time through a simple strategy.

Chapter
Discussing the Valuation of Social Networks
Episode
"Sara's List" Update: 12 Startups Where Stock Grants Will Make You A Millionaire
Podcast
My First Million
Social media use has a correlation of 0.15 which can potentially explain the mental health epidemic affecting millions of children, according to Jonathan Haidt.
29:51 - 30:35 (00:43)
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Social Media
Summary

Social media use has a correlation of 0.15 which can potentially explain the mental health epidemic affecting millions of children, according to Jonathan Haidt.

Chapter
Social Media Use and Mental Health in Kids
Episode
#291 – Jonathan Haidt: The Case Against Social Media
Podcast
Lex Fridman Podcast
Climate-related disaster deaths have decreased by 98% over the last century, with very little attention given to the commendable technologies and strategies that have helped reduce these deaths.
1:05:17 - 1:07:10 (01:53)
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Climate Change
Summary

Climate-related disaster deaths have decreased by 98% over the last century, with very little attention given to the commendable technologies and strategies that have helped reduce these deaths.

Chapter
Debunking Malaria’s Decrease by Analogizing it to Climate Change
Episode
#324 - Alex Epstein - Can Fossil Fuels Save The World?
Podcast
Modern Wisdom
The speaker discusses their strategy for making a comfortable income in tech, without having to rely on a traditional salary job.
49:06 - 50:58 (01:52)
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Tech Careers
Summary

The speaker discusses their strategy for making a comfortable income in tech, without having to rely on a traditional salary job. They suggest reading tech news and keeping up to date on new platform launches to find opportunities to make money.

Chapter
Bootstrapping Product Hunt with Ryan Hoover
Episode
Greatest Hits #4 - How To Sell Your Company for $750M - Meet Vungle's Jack Smith
Podcast
My First Million
Early detection of cancer has better outcomes than treating the same cancer later on down the line with the same cocktail of drugs.
1:55:39 - 2:00:30 (04:51)
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Cancer treatment
A father describes how he used myceliated rice to get rid of carpenter ants in his home, thanks to his daughter's toy dish.
28:53 - 30:58 (02:04)
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Fungi
Summary

A father describes how he used myceliated rice to get rid of carpenter ants in his home, thanks to his daughter's toy dish.

Chapter
The Science of Bugs and Fungi
Episode
#340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World
Podcast
The Tim Ferriss Show
The speaker discusses managing wealth and the risks involved in investing in individual stocks.
55:06 - 56:42 (01:36)
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Wealth Management
While certain molecules and blood components can be accurately measured with a small droplet of blood using sophisticated machines, the technology to replace comprehensive blood panels used in routine check-ups is not yet within reach.
11:53 - 17:47 (05:53)
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Healthcare Technology
Summary

While certain molecules and blood components can be accurately measured with a small droplet of blood using sophisticated machines, the technology to replace comprehensive blood panels used in routine check-ups is not yet within reach.

Chapter
What Can We Detect From a Single Drop of Blood Today?
Episode
E62: Elizabeth Holmes verdict, fraud origins & takeaways, navigating "The Great Markdown" & more
Podcast
All-In with Chamath, Jason, Sacks & Friedberg
Despite common belief, studies show no link between sugar and hyperactivity in children at a population level.
14:40 - 17:31 (02:50)
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Sugar, Hyperactivity, Alcohol, Culture
Summary

Despite common belief, studies show no link between sugar and hyperactivity in children at a population level. Additionally, cultural differences affect how alcohol consumption is perceived and can lead to varying social behaviors and violence.

Chapter
Myth Busting: Sugar and Hyperactivity
Episode
The Trouble with Sugar
Podcast
Maintenance Phase
This podcast discusses the hidden inflation of the US dollar, which has been approximately 7% a year for the past century, though this figure is never acknowledged by government or conventional economists.
26:50 - 31:29 (04:38)
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US Dollar
Summary

This podcast discusses the hidden inflation of the US dollar, which has been approximately 7% a year for the past century, though this figure is never acknowledged by government or conventional economists.

Chapter
The Relationship between Money Supply Expansion and Investment Returns
Episode
#276 – Michael Saylor: Bitcoin, Inflation, and the Future of Money
Podcast
Lex Fridman Podcast
Asset allocation might not matter much for your investment unless there are exceptional scenarios like the current drop in the tech stocks or Bitcoin.
17:21 - 19:35 (02:14)
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Investment
Summary

Asset allocation might not matter much for your investment unless there are exceptional scenarios like the current drop in the tech stocks or Bitcoin.

Chapter
Practicality of Savings and Investing During Bitcoin Volatility
Episode
#462 - Nick Maggiulli - The Best Way To Build Your Personal Wealth
Podcast
Modern Wisdom