Episode

Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
listen on Spotify
1:20:56
Published: Tue Jun 10 2014
Description

My guest this episode is Rhonda Perciavalle Patrick, Ph.D., who works with Dr. Bruce Ames, the 23rd most-cited scientist across ALL fields between 1973 and 1984 (!).Dr. Patrick also conducts clinical trials, performed aging research at Salk Institute for Biological Studies, and did graduate research at St. Jude Children’s Research Hospital, where she focused on cancer, mitochondrial metabolism, and apoptosis. Whether you want to extend life, buy a stem-cell "insurance policy," or guard against cancer and premature death, she will have a surprise insight for you.Find her on Twitter at @foundmyfitness.Enjoy! Tim***If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to convince hard-to-get guests. I also love reading the reviews!For show notes and past guests, please visit tim.blog/podcast.Sign up for Tim’s email newsletter (“5-Bullet Friday”) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Interested in sponsoring the podcast? Visit tim.blog/sponsor and fill out the form.Discover Tim’s books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissFacebook: facebook.com/timferriss YouTube: youtube.com/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Chapters
This podcast episode explores the world of biohacking, performance enhancement, and the promises and dangers of supplements.
00:00 - 02:42 (02:42)
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Biohacking
Summary

This podcast episode explores the world of biohacking, performance enhancement, and the promises and dangers of supplements. The Athletic Greens all-in-one formula is recommended for its 75 vitamins, minerals, and whole food sourced ingredients.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
Dr. Rhonda Patrick talks about clinical trials, aging research, quantifying different levels of minerals, vitamins, and hormones to enhance longevity, and shares valuable insights on healthspan.
02:43 - 06:34 (03:51)
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healthspan
Summary

Dr. Rhonda Patrick talks about clinical trials, aging research, quantifying different levels of minerals, vitamins, and hormones to enhance longevity, and shares valuable insights on healthspan.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
The speaker discusses her experience with jumping rope and how micronutrient deficiencies can cause insidious damage that leads to age-related diseases later in life, emphasizing the importance of preventative medicine and getting essential minerals and vitamins.
06:34 - 12:12 (05:37)
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Preventative Medicine
Summary

The speaker discusses her experience with jumping rope and how micronutrient deficiencies can cause insidious damage that leads to age-related diseases later in life, emphasizing the importance of preventative medicine and getting essential minerals and vitamins.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
Micronutrient inadequacy does not necessarily lead to a clinical manifestation of deficiency.
12:12 - 17:03 (04:51)
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Micronutrients
Summary

Micronutrient inadequacy does not necessarily lead to a clinical manifestation of deficiency. Proteins that require micronutrients for short-term survival get their pick first, whereas ones like enzymes involved in DNA repair, which repair DNA damage, well, DNA damage accumulates over time and that doesn't end, you know, have a problem until the fifth or sixth decade in your life.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
Getting adequate intake of micronutrients like magnesium and vitamin K can prevent health issues such as inadequate DNA repair and calcification in arteries.
17:04 - 19:47 (02:43)
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Micronutrients
Summary

Getting adequate intake of micronutrients like magnesium and vitamin K can prevent health issues such as inadequate DNA repair and calcification in arteries.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
The guest speaker discusses the misconceptions and exaggerated claims about the paleo diet, including the beliefs about phytic acid and saponins, and the concern over consuming too many vegetables.
19:47 - 22:55 (03:08)
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Paleo Diet
Summary

The guest speaker discusses the misconceptions and exaggerated claims about the paleo diet, including the beliefs about phytic acid and saponins, and the concern over consuming too many vegetables.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
People who are unhealthy due to a disease like cancer, runs the risk of worsening their condition by taking supplements as cancer cells require the same nutrients as healthy cells, albeit in more quantities, which may fuel the proliferation of cancer cells.
22:56 - 30:58 (08:02)
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Supplements
Summary

People who are unhealthy due to a disease like cancer, runs the risk of worsening their condition by taking supplements as cancer cells require the same nutrients as healthy cells, albeit in more quantities, which may fuel the proliferation of cancer cells.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
Folate is essential for a good immune system, especially for eliminating pre-cancer cells.
30:58 - 36:53 (05:55)
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Folate, Immune system
Summary

Folate is essential for a good immune system, especially for eliminating pre-cancer cells. Its adequacy enables the body to fight cancer, and a deficiency can cause devastating consequences.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
Hormesis is a response in which a little bit of stress is induced in the body, leading to activation of genes involved in stress resistance.
36:53 - 41:15 (04:22)
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Health
Summary

Hormesis is a response in which a little bit of stress is induced in the body, leading to activation of genes involved in stress resistance. It is a way to get benefits like greater thermic effect of food and better cognitive function without a higher protein diet.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
The paleo diet is examined through the lens of molecular biology, including the impact of protein and IGF-1 on the body and how micronutrients can help repair damage.
41:15 - 45:13 (03:58)
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Paleo Diet
Summary

The paleo diet is examined through the lens of molecular biology, including the impact of protein and IGF-1 on the body and how micronutrients can help repair damage. Some studies suggest that people who eat a paleo-like diet have lower levels of inflammation.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
A discussion on the role of methylation and the SAM cycle in creating methyl groups for epigenetic marks which can impact gene expression and overall health.
45:13 - 49:04 (03:50)
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Methylation
Summary

A discussion on the role of methylation and the SAM cycle in creating methyl groups for epigenetic marks which can impact gene expression and overall health.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
Listen to an exploration of epigenetics, the study of how environmental and behavioral factors can affect gene expression, and the potential impact it has on future generations.
49:04 - 51:45 (02:41)
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Epigenetics
Summary

Listen to an exploration of epigenetics, the study of how environmental and behavioral factors can affect gene expression, and the potential impact it has on future generations.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
Researchers have been able to identify human age with 96% accuracy within four years by analyzing DNA methylation patterns from blood cells.
51:45 - 56:00 (04:15)
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DNA methylation
Summary

Researchers have been able to identify human age with 96% accuracy within four years by analyzing DNA methylation patterns from blood cells. The patterns change as we age due to factors such as inflammation and oxidative stress.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
The idea of banking and harvesting stem cells for later use is becoming a popular practice.
56:00 - 59:33 (03:32)
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Stem Cells
Summary

The idea of banking and harvesting stem cells for later use is becoming a popular practice. With advancements in stem cell research, scientists are also learning how to reprogram stem cells, providing even more possibilities for use in the future.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
Dental pulp stem cells can form bone, cartilage, and even teeth.
59:33 - 1:02:44 (03:10)
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Stem Cells
Summary

Dental pulp stem cells can form bone, cartilage, and even teeth. Researchers have found they can also help regenerate bone and repair spinal cord injuries in animal models and humans.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
This transcript snippet explains the differences between pluripotent, multipotent and mesenchymal stem cells, with an example of how bone marrow cells can form blood cells.
1:02:44 - 1:04:53 (02:08)
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Stem Cells
Summary

This transcript snippet explains the differences between pluripotent, multipotent and mesenchymal stem cells, with an example of how bone marrow cells can form blood cells.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
Exploring new possibilities of gene therapy and stem cells, this podcast discusses the recent developments in gene expression research and how it relates to self-driving cars.
1:04:53 - 1:10:13 (05:19)
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Gene Expression
Summary

Exploring new possibilities of gene therapy and stem cells, this podcast discusses the recent developments in gene expression research and how it relates to self-driving cars.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
The body needs various minerals and vitamins as cofactors for the hundreds of enzymes that function within it.
1:10:13 - 1:12:43 (02:30)
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nutrition
Summary

The body needs various minerals and vitamins as cofactors for the hundreds of enzymes that function within it. The Vitamix is an easy way of ensuring a regular intake of these nutrients.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
Instead of focusing on the small, possibly negative aspects of our diet, we should focus on what our body needs to function properly, which includes a variety of plant-based foods that contain natural pesticides and insecticides.
1:12:43 - 1:18:55 (06:12)
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Nutrition
Summary

Instead of focusing on the small, possibly negative aspects of our diet, we should focus on what our body needs to function properly, which includes a variety of plant-based foods that contain natural pesticides and insecticides. Starting with small behavior changes can be more effective than overwhelming oneself with a long list of dietary restrictions.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show
The body needs essential nutrients to cope up with DNA damage, metabolic processes and immune function, which produces inflammatory molecules as a result of normal living.
1:18:55 - 1:20:51 (01:56)
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Health and Wellness
Summary

The body needs essential nutrients to cope up with DNA damage, metabolic processes and immune function, which produces inflammatory molecules as a result of normal living.

Episode
Ep. 12: Dr. Rhonda Patrick on Life Extension, Performance, and More
Podcast
The Tim Ferriss Show