Episode
#239: How to Reverse Aging with Art De Vany
Description
Dr. Arthur De Vany is nearly eighty years old and ripped. Better known as Art De Vany, he was signed as a professional baseball player in his youth and later earned his Ph.D. in Economics at UCLA. He is most famous for his "evolutionary fitness" approach to training and diet, and our conversation focuses on that. During his time at UCLA, Art did many things, including creating mathematical and statistical models to precisely describe the motion picture market. Art is Professor Emeritus of Economics of the University of California, Irvine, and is a member of its acclaimed Institute for Mathematical Behavioral Sciences. A lifelong student of metabolism and fitness, Art has lived as a Paleo athlete for more than thirty years and is considered a "patriarch" of the Paleo movement. He believes there is no such thing as "healthy" aging and that we can intervene to protect against the aging process. In this episode, we talk about his daily schedule, workout routines, why he never gets sick, ice ages, economics, philosophies of intermittent everything, and really dig into the details of a fascinating man. Enjoy! Show notes and links for this episode can be found at www.fourhourworkweek.com/podcast. This podcast is brought to you by Four Sigmatic. I reached out to these Finnish entrepreneurs after a very talented acrobat introduced me to one of their products, which blew my mind (in the best way possible). It is mushroom coffee featuring chaga. It tastes like coffee, but there are only 40 milligrams of caffeine, so it has less than half of what you would find in a regular cup of coffee. I do not get any jitters, acid reflux, or any type of stomach burn. It put me on fire for an entire day, and I only had half of the packet. People are always asking me what I use for cognitive enhancement right now -- this is the answer. You can try it right now by going to foursigmatic.com/tim and using the code Tim to get 20 percent off your first order. If you are in the experimental mindset, I do not think you'll be disappointed. This podcast is also brought to you by Audible. I have used Audible for years, and I love audiobooks. I have two to recommend: The Graveyard Book by Neil Gaiman Vagabonding by Rolf Potts All you need to do to get your free 30-day Audible trial is go to Audible.com/Tim. Choose one of the above books, or choose any of the endless options they offer. That could be a book, a newspaper, a magazine, or even a class. It's that easy. Go to Audible.com/Tim and get started today. Enjoy. ***If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to convince hard-to-get guests. I also love reading the reviews!For show notes and past guests, please visit tim.blog/podcast.Sign up for Tim’s email newsletter (“5-Bullet Friday”) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Interested in sponsoring the podcast? Visit tim.blog/sponsor and fill out the form.Discover Tim’s books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissFacebook: facebook.com/timferriss YouTube: youtube.com/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Chapters
This transcript is a collection of random quotes from various sources, including personal reflections, motivational speeches, and podcasts.
00:00 - 01:07 (01:07)
Summary
This transcript is a collection of random quotes from various sources, including personal reflections, motivational speeches, and podcasts.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
In this episode, the host shares how he meets podcast guests and talks about individuals who truly live up to their ideologies.
01:07 - 10:58 (09:51)
Summary
In this episode, the host shares how he meets podcast guests and talks about individuals who truly live up to their ideologies. He also talks about his guest's daily routine, workout regimes, and why he never gets sick.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The episode discusses the issues with using revenue as the sole indicator of success, such as in the case of authorship and movie-making, and highlights the importance of focusing on quality over quantity.
10:58 - 19:59 (09:00)
Summary
The episode discusses the issues with using revenue as the sole indicator of success, such as in the case of authorship and movie-making, and highlights the importance of focusing on quality over quantity.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The sea squirt finds a location to live, latches on and eats its brain since it no longer needs to move around to find food.
19:59 - 24:02 (04:03)
Summary
The sea squirt finds a location to live, latches on and eats its brain since it no longer needs to move around to find food. The brain is dispensable and every bit of protein and substrate is best used as nutrients for consumption.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
Losing cell function and integrity can reduce the body's ability to renew tissues, as immune pathways intersect with cell defense pathways.
24:02 - 32:46 (08:44)
Summary
Losing cell function and integrity can reduce the body's ability to renew tissues, as immune pathways intersect with cell defense pathways. Signaling to affect proteostasis in the brain can send defensive neural signals to other tissues, rather than signals for growth.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The evolution of the human skull led to a more juvenileized version of earlier skulls, likely due to the need to store nutrients during times of food scarcity.
32:46 - 36:32 (03:45)
Summary
The evolution of the human skull led to a more juvenileized version of earlier skulls, likely due to the need to store nutrients during times of food scarcity. While there are about a billion proteins in a cell, making of new proteins is an interval-based process.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The productivity of stem cells seems to depend on the individuals who contain them.
36:32 - 43:01 (06:29)
Summary
The productivity of stem cells seems to depend on the individuals who contain them. Doubling the number of stem cells that flood out may exhaust them because the ones in the niche may already be depleted.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The speaker emphasizes the importance of maintaining proper posture while working out, and using equipment such as leg extensions to achieve it.
43:01 - 46:18 (03:17)
Summary
The speaker emphasizes the importance of maintaining proper posture while working out, and using equipment such as leg extensions to achieve it.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
Stretching your muscles can help activate the Titan protein, leading to stronger and fuller muscles that are faster when contracted.
46:18 - 50:17 (03:59)
Summary
Stretching your muscles can help activate the Titan protein, leading to stronger and fuller muscles that are faster when contracted.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
Eating carbohydrates is important to burn off fat as it is the first source of fuel that the body uses.
50:17 - 56:43 (06:26)
Summary
Eating carbohydrates is important to burn off fat as it is the first source of fuel that the body uses. Fat is used as the last option and only after carbohydrates and protein have been burned off.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The speaker discusses the misconception of throwing away egg yolks and how consuming whole eggs can benefit the body's tissue-building process.
56:43 - 1:04:34 (07:51)
Summary
The speaker discusses the misconception of throwing away egg yolks and how consuming whole eggs can benefit the body's tissue-building process. They also touch on the topic of post-workout nutrition.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The insulin-like peptides can signal in the brain and taking glucose disposal burden off the other cells can turn that down.
1:04:34 - 1:10:20 (05:46)
Summary
The insulin-like peptides can signal in the brain and taking glucose disposal burden off the other cells can turn that down. A study by Isomura showed a connection between ribosomes and fast-twitch fibers.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The Foxo window is a part of a good sleep pattern that allows for rebuilding tissues.
1:10:20 - 1:15:51 (05:30)
Summary
The Foxo window is a part of a good sleep pattern that allows for rebuilding tissues. To focus on the Foxo window, one should avoid eating four to five hours before going to bed.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The key to overcoming depression and post-traumatic stress is to heal the brain by growing neurotrophic factors, instead of trying to think your way out of the problem.
1:15:51 - 1:20:12 (04:21)
Summary
The key to overcoming depression and post-traumatic stress is to heal the brain by growing neurotrophic factors, instead of trying to think your way out of the problem. People who constantly ruminate or rehearse the same negative thoughts develop stronger negative circuits, leading to depression and trauma, according to Naval Ravikant.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
Nassim Taleb has helped inform the concept of investing with a barbell strategy, which means having the majority of investments in cash or its equivalents and a small portion in high-risk/high-reward opportunities.
1:20:12 - 1:28:26 (08:14)
Summary
Nassim Taleb has helped inform the concept of investing with a barbell strategy, which means having the majority of investments in cash or its equivalents and a small portion in high-risk/high-reward opportunities. This approach utilizes the upper tail to pay for the lower tail.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
This podcast discusses the significance of the hypothalamus pituitary testosterone axis (HPTA) and the potential disruption caused by testosterone or luteinizing hormone supplements.
1:28:26 - 1:33:18 (04:52)
Summary
This podcast discusses the significance of the hypothalamus pituitary testosterone axis (HPTA) and the potential disruption caused by testosterone or luteinizing hormone supplements. The discussion also mentions concerns about potential tolerance development and side effects from chronic use of melatonin.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The speaker talks about the evolutionary fitness movement and how living a simple, clean, decent life and eating good food can mimic historical patterns of living and potentially lead to a healthier lifestyle.
1:33:18 - 1:38:25 (05:07)
Summary
The speaker talks about the evolutionary fitness movement and how living a simple, clean, decent life and eating good food can mimic historical patterns of living and potentially lead to a healthier lifestyle. He also mentions the idea that much of what we think we know may be wrong, and that it's important to acknowledge that nature knows more than we do.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The speaker discusses the process of finding and choosing relevant literature to research a topic with a focus on science, citing a personal bibliography of 8000 entries in aging literature.
1:38:25 - 1:41:18 (02:53)
Summary
The speaker discusses the process of finding and choosing relevant literature to research a topic with a focus on science, citing a personal bibliography of 8000 entries in aging literature.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
Research on aging suggests that switches and windows play a significant role in systemic signaling and the ability to renew cells and rebuild tissues.
1:41:18 - 1:46:37 (05:19)
Summary
Research on aging suggests that switches and windows play a significant role in systemic signaling and the ability to renew cells and rebuild tissues. In addition to lightweight sets and low-repetition exercises, warm-ups can also help minimize injury risks.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The podcast host and guest discuss the economics of extreme climate events and how someone could self-educate on the topic, as it's not typically taught in schools.
1:46:37 - 1:50:34 (03:57)
Summary
The podcast host and guest discuss the economics of extreme climate events and how someone could self-educate on the topic, as it's not typically taught in schools.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The speaker reflects on the scientific quest of aging, discussing topics such as the nature of pores, economics, workouts to lift heavy things, freedom in markets, and arbitrage opportunities.
1:50:34 - 1:54:25 (03:51)
Summary
The speaker reflects on the scientific quest of aging, discussing topics such as the nature of pores, economics, workouts to lift heavy things, freedom in markets, and arbitrage opportunities.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
The speaker is promoting Audible to the listeners of the podcast, offering a free 30 day trial for those who go to audible.com/Tim, where they can choose from a selection of books.
1:54:25 - 1:58:28 (04:03)
Summary
The speaker is promoting Audible to the listeners of the podcast, offering a free 30 day trial for those who go to audible.com/Tim, where they can choose from a selection of books.
Episode#239: How to Reverse Aging with Art De Vany
PodcastThe Tim Ferriss Show
Four Sigmatic offers mushroom coffee and elixirs that contain less than half of the caffeine found in regular coffee, providing a unique and enjoyable drinking experience.
1:58:28 - 1:59:30 (01:02)
Summary
Four Sigmatic offers mushroom coffee and elixirs that contain less than half of the caffeine found in regular coffee, providing a unique and enjoyable drinking experience. To try their products, visit foursigmatic.com/tim and use the code TIM for a 20% discount on your first order.