Episode

GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
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3:48:52
Published: Wed Feb 01 2023
Description

This is episode 3 of a 6-part special series on fitness, exercise and performance with Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton. He explains protocols to improve the various kinds of physical endurance: muscular endurance, anerobic capacity, maximum aerobic output, and long duration endurance. He also explains how the body uses different energy sources (carbohydrates, proteins, fats) during rest and exercise. He also explains the mechanisms underlying fat loss and how and why exercise accelerates rates of fat loss. We cover the many concepts related to endurance training and fat loss such as metabolic flexibility, breathwork training for exercise performance and recovery, lactate production and regulation, how to improve blood flow to muscles, anaerobic vs. aerobic metabolism, exercise fatigue, low-carbohydrate diets and fat loss, and how to combine different types of workouts to improve overall endurance. This episode in intended for everyone ranging from novice and recreational exercisers to elite endurance athletes. Anyone wishing to improve their physical health and performance stands to benefit from the information. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman LMNT: https://drinklmnt.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Endurance: Benefits, Mechanics & Breathing  (00:07:30) Tool: “Exercise Snacks” (00:14:21) Momentous, Levels, LMNT (00:18:01) Endurance Categories (00:22:16) Fat Loss & Respiration; Carbon Cycles & Storage, Metabolism (00:33:08) Exhalation Rates, Exercise & Fat Loss; Calories (00:41:47) Cardiovascular Adaptations, Cardiac Output & Maximum Heart Rate (00:47:03) AG1 (Athletic Greens) (00:47:55) Excess Post-Exercise Consumption (EPOC); Exercise Intensity & Fat vs. Carbohydrate Energy Utilization (00:59:35) Tool: Training for Fat Loss, Carbohydrate Stores, Liver Glycogen & Fatigue (01:08:01) Metabolic Flexibility, Carbohydrates & Fat; Exercise & Flexible Fuel Utilization  (01:16:07) Muscle & Basal Metabolic Rate (01:19:40) InsideTracker (01:20:43) Assessing Metabolic Flexibility, Blood Glucose, Carbohydrates (01:27:48) Caffeine, High-Carbohydrate Meals & Timing, Managing Daily Energy  (01:36:42) Cellular Energy (ATP) Production from Carbs; Lactate; Anerobic, Aerobic (01:50:45) Lactate, Energy Production Buffer (01:53:14) Fuel Sources & Exercise; Mitochondria, Oxygen Availability & Lactate (02:02:50) Lactate for Exercise & Cognitive Performance (02:04:33) Energy Production, Waste Management & Endurance Exercise; Insulin (02:12:49) Protein & Fat Utilization for Energy; Exercise & Fat Loss (02:21:20) Protein as Fuel Source, Fire Analogy  (02:26:39) Low-Carbohydrate Diet & Performance (02:29:40) Muscular Endurance: Fuel Sources, Training & Capillarization (02:37:30) Tool: Muscular Endurance & Modifiable Variables; Examples (02:45:07) Anerobic Capacity: Fuel Sources, Training & Oxygen Utilization  (02:49:23) Tool: Cardiac Output, Heart Rate Zones & Breathing “Gear System” (02:58:10) Tool: Anerobic Capacity & Modifiable Variables; Examples, Nasal Recovery (03:11:45) Tool: “Sugarcane” Endurance Protocol  (03:14:02) Anerobic Capacity, Training Progression  (03:16:40) Tool: Maximum Aerobic Output, Training & Modifiable Variables (03:21:58) Tool: Long Duration Endurance, Training, Circuits (03:25:13) Long Duration Endurance, Capillarization, Fatigue & Breathwork, Technique (03:29:10) Weekly Combination Training, Metabolic Flexibility & Longevity (03:37:23) Tool: Mixed Endurance Training, Half Marathon Example (03:47:33) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

Chapters
In this podcast, the hosts discuss the various ways to trigger the endurance adaptation and achieve the four different types of endurance while maximizing fat loss.
00:00 - 01:39 (01:39)
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Endurance
Summary

In this podcast, the hosts discuss the various ways to trigger the endurance adaptation and achieve the four different types of endurance while maximizing fat loss. They also explore the definition of endurance and the different protocols required for it.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The belief that cardio exercise is only for losing fat and for short term health benefits is a myth, and endurance training must be practiced with the goal of long term sustainability.
01:39 - 07:22 (05:43)
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Endurance Training
Summary

The belief that cardio exercise is only for losing fat and for short term health benefits is a myth, and endurance training must be practiced with the goal of long term sustainability. There are tools and mechanisms that can help access better endurance.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
Learn how running up a flight of stairs or doing a quick bout of exercise for just 20 seconds can be an effective mitigation strategy for those stuck in a sedentary lifestyle.
07:22 - 13:13 (05:50)
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Physical Fitness
Summary

Learn how running up a flight of stairs or doing a quick bout of exercise for just 20 seconds can be an effective mitigation strategy for those stuck in a sedentary lifestyle.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
Levels is a tool that helps users understand how various factors, such as food intake and exercise, impact their blood glucose levels.
13:13 - 18:09 (04:55)
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Blood Glucose Levels
Summary

Levels is a tool that helps users understand how various factors, such as food intake and exercise, impact their blood glucose levels. Additionally, the tool provides insights on how to optimize mental and physical performance based on nutrient intake and lifestyle habits.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The podcast delves into how the body makes and handles energy and fatigue, discussing fuel sources including glycogen and body fat, along with how protein functions as a fuel source.
18:09 - 26:47 (08:38)
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Energy metabolism
Summary

The podcast delves into how the body makes and handles energy and fatigue, discussing fuel sources including glycogen and body fat, along with how protein functions as a fuel source.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The length and degree of saturation of fatty acids are determined by the number and location of double bonds in their carbon chains, which require energy from the sun to form.
26:47 - 30:30 (03:43)
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Fatty Acids
Summary

The length and degree of saturation of fatty acids are determined by the number and location of double bonds in their carbon chains, which require energy from the sun to form.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The podcast delves into the process of how humans lose fat and explores whether breath protocols that force exhale can help in burning fat.
30:30 - 37:58 (07:27)
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Fat loss
Summary

The podcast delves into the process of how humans lose fat and explores whether breath protocols that force exhale can help in burning fat.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
Increasing respiration rate is the key to optimizing fat loss, regardless of the exact protocol for training.
37:58 - 42:44 (04:45)
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Fat loss
Summary

Increasing respiration rate is the key to optimizing fat loss, regardless of the exact protocol for training. It is also possible to increase lung capacity for even more respiration and better fat loss results.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The amount of blood pumped out per pump, called stroke volumes, increase when you're able to adapt to endurance training, which reduces your heart rate and keeps cardiac output exact to energetic demands.
42:44 - 47:03 (04:19)
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Cardiovascular System
Summary

The amount of blood pumped out per pump, called stroke volumes, increase when you're able to adapt to endurance training, which reduces your heart rate and keeps cardiac output exact to energetic demands.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The different modes of energy utilization in the body, including making and breaking energy bonds, moving energy into different tissues, and exhalation, all relate to different modes of movement and exercise.
47:03 - 53:34 (06:30)
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Energy Utilization
Summary

The different modes of energy utilization in the body, including making and breaking energy bonds, moving energy into different tissues, and exhalation, all relate to different modes of movement and exercise. This results in excess post exercise oxygen consumption (EPOC).

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
Burning fat during exercise does not necessarily mean burning body fat stores.
53:34 - 1:03:53 (10:19)
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fat loss
Summary

Burning fat during exercise does not necessarily mean burning body fat stores. Maximizing fat burning for exercise and maximizing body fat loss over time are different goals.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
During exercise, the body breaks down glycogen to maintain blood glucose levels and prevent a drop in blood pH, glucose, pressure, and electrolyte concentrations.
1:03:53 - 1:06:57 (03:03)
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Exercise
Summary

During exercise, the body breaks down glycogen to maintain blood glucose levels and prevent a drop in blood pH, glucose, pressure, and electrolyte concentrations. The liver also plays a crucial role in stabilizing blood glucose levels.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The issue of accessing body fat stores during a subcaloric state and using body fat converted to glycogen to fill glycogen stores is discussed.
1:06:57 - 1:12:08 (05:10)
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Fat Loss
Summary

The issue of accessing body fat stores during a subcaloric state and using body fat converted to glycogen to fill glycogen stores is discussed. When muscle glycogen is burned and a person is hypo caloric, the result is fat loss.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The idea of being "fat adapted" is often misunderstood and exaggerated.
1:12:08 - 1:19:05 (06:57)
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Fat adaptation
Summary

The idea of being "fat adapted" is often misunderstood and exaggerated. Adding more muscle might not be significant if you already have enough muscle mass, and other factors play a more critical role in building muscle.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
Learn about the ideal range for blood glucose levels and how symptomology can help diagnose uncontrolled energy bouts and mood swings.
1:19:05 - 1:26:13 (07:07)
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Health
Summary

Learn about the ideal range for blood glucose levels and how symptomology can help diagnose uncontrolled energy bouts and mood swings. Additionally, discover the limitations of traditional blood and DNA tests.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
Ingesting carbohydrates late at night can potentially fill glycogen stores and provide energy for morning training, despite traditional advice to avoid carbohydrates late in the day, and can promote better sleep due to the sedating effects.
1:26:13 - 1:31:17 (05:03)
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Nutrition
Summary

Ingesting carbohydrates late at night can potentially fill glycogen stores and provide energy for morning training, despite traditional advice to avoid carbohydrates late in the day, and can promote better sleep due to the sedating effects. High carbohydrate meals at the end of the day can also aid with weight-cutting for athletes.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The key to managing energy throughout the day includes stabilizing protein and ingesting food in proper combinations with fiber and protein.
1:31:17 - 1:35:57 (04:40)
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Energy Management
Summary

The key to managing energy throughout the day includes stabilizing protein and ingesting food in proper combinations with fiber and protein. Implementing strategies like pre-exercise carbohydrate meal and fat prior to the workout can also help in enhancing adaptation and managing energy.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
This podcast segment explains how glycogen is split and provides a brief overview of the energy that can be obtained from it.
1:35:57 - 1:42:44 (06:46)
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Glycogen
Summary

This podcast segment explains how glycogen is split and provides a brief overview of the energy that can be obtained from it.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The number and quality of mitochondria impact anaerobic performance due to their role in producing energy quickly and limiting acidity.
1:42:45 - 1:48:44 (05:58)
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Athletic Performance
Summary

The number and quality of mitochondria impact anaerobic performance due to their role in producing energy quickly and limiting acidity. The efficiency of this system can impact high-intensity activities.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The body has different systems for producing the energy needed to move, including creatine, anaerobic glycolysis, and fat metabolism, with each system providing energy for different time frames.
1:48:44 - 1:56:58 (08:14)
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Energy Systems
Summary

The body has different systems for producing the energy needed to move, including creatine, anaerobic glycolysis, and fat metabolism, with each system providing energy for different time frames.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The three-carbon molecule known as pyruvate plays a critical role in cellular respiration, as it acts as a fork in the road leading to either the production of energy or the formation of metabolic waste.
1:56:58 - 2:03:54 (06:55)
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Pyruvate
Summary

The three-carbon molecule known as pyruvate plays a critical role in cellular respiration, as it acts as a fork in the road leading to either the production of energy or the formation of metabolic waste.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
Ingesting carbohydrates before a short endurance event such as a half marathon may not be necessary, while long endurance events such as cycling may require the use of fat as fuel sources.
2:03:54 - 2:08:10 (04:16)
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Endurance Athletics
Summary

Ingesting carbohydrates before a short endurance event such as a half marathon may not be necessary, while long endurance events such as cycling may require the use of fat as fuel sources.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
When striving to achieve peak performance during endurance activities, it's important to focus on breathing, heart rate, and glycogen stores.
2:08:10 - 2:13:50 (05:39)
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Endurance Exercise
Summary

When striving to achieve peak performance during endurance activities, it's important to focus on breathing, heart rate, and glycogen stores. For longer events, running out of muscle or liver glycogen can become a concern.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
Whether it's fat or carbohydrates, they ultimately end up in the mitochondria as the same thing for energy use, but pulling energy from fat means having to draw from the entire body, resulting in overall fat loss.
2:13:50 - 2:18:38 (04:48)
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Weight loss
Summary

Whether it's fat or carbohydrates, they ultimately end up in the mitochondria as the same thing for energy use, but pulling energy from fat means having to draw from the entire body, resulting in overall fat loss. Small chain and medium chain fatty acids, such as MCT, can be utilized immediately as an energy source.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
When it comes to burning calories and losing fat, it doesn't matter whether you rely predominantly on carbohydrate, fat or protein.
2:18:38 - 2:24:06 (05:28)
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exercise
Summary

When it comes to burning calories and losing fat, it doesn't matter whether you rely predominantly on carbohydrate, fat or protein. Different types of exercise may make you hungrier than others for a variety of reasons, but the key to fat loss is really just creating a caloric deficit.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
A high fat, low carbohydrate nutrition strategy is effective for people who don't do much physical activity.
2:24:06 - 2:29:58 (05:51)
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Nutrition Strategy
Summary

A high fat, low carbohydrate nutrition strategy is effective for people who don't do much physical activity. Those who consume very low or zero carbohydrate diets tend to do limited or low-intensity endurance exercise and are not able to solely rely on fat as their energy source.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
This podcast episode discusses the different exercise adaptations, starting with muscular endurance, which is generally present in local muscle groups and causes pain when used excessively.
2:29:58 - 2:34:01 (04:03)
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Exercise Adaptations
Summary

This podcast episode discusses the different exercise adaptations, starting with muscular endurance, which is generally present in local muscle groups and causes pain when used excessively.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
Muscle endurance training increases the number of capillaries in the muscle which can lead to better muscle performance.
2:34:01 - 2:39:03 (05:02)
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Muscle Endurance Training
Summary

Muscle endurance training increases the number of capillaries in the muscle which can lead to better muscle performance. The specific signal that causes this increase is still unknown.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
This episode discusses the importance of training for muscle endurance and provides tips on how to effectively train for it without sacrificing muscle strength and hypertrophy.
2:39:03 - 2:43:47 (04:43)
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muscle endurance
Summary

This episode discusses the importance of training for muscle endurance and provides tips on how to effectively train for it without sacrificing muscle strength and hypertrophy.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
Even if you're an endurance athlete or a recreational exerciser not interested in building more muscle speed, increases in anaerobic capacity are still beneficial since it helps prevent running out of muscle glycogen during long periods of exercise.
2:43:47 - 2:48:48 (05:01)
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Anaerobic Capacity
Summary

Even if you're an endurance athlete or a recreational exerciser not interested in building more muscle speed, increases in anaerobic capacity are still beneficial since it helps prevent running out of muscle glycogen during long periods of exercise. Anaerobic exercises such as wall sits and pushups are effective and can be done in intervals for maximum benefit.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The podcast discusses the back-of-the-envelope method and the more precise method of dividing your heart rate zones from one to five.
2:48:48 - 2:54:20 (05:31)
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Heart Rate, Exercise
Summary

The podcast discusses the back-of-the-envelope method and the more precise method of dividing your heart rate zones from one to five. They also review Brian Mackenzie's breathing gear system to help assess your heart rate zones.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The podcast discusses the different gear levels in breathing techniques for high-intensity intervals, which range from nose to mouth strategy to straight mouth breathing, which is necessary for maximum exertion.
2:54:20 - 3:00:20 (06:00)
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Breathing Techniques
Summary

The podcast discusses the different gear levels in breathing techniques for high-intensity intervals, which range from nose to mouth strategy to straight mouth breathing, which is necessary for maximum exertion.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The speaker suggests picking total body movements like pushing or dragging a sled, sprinting uphill or swimming for workouts.
3:00:20 - 3:03:29 (03:08)
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Total Body Movements
Summary

The speaker suggests picking total body movements like pushing or dragging a sled, sprinting uphill or swimming for workouts. The speaker also explains the benefits of the assault bike and suggests looking for exercises that provide high resistance and low eccentric load.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
A minimum of 4 rounds of 30 seconds on, 30 seconds off protocol of high-intensity interval training (HIIT) 3 days a week is recommended.
3:03:29 - 3:10:41 (07:12)
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Fitness
Summary

A minimum of 4 rounds of 30 seconds on, 30 seconds off protocol of high-intensity interval training (HIIT) 3 days a week is recommended. The protocol consists of an air bike one day, hill sprints another day, and swimming on the third day.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The interviewee explains his training method, which involves multiple rounds of high-intensity exercises with short rest periods.
3:10:41 - 3:14:21 (03:39)
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Fitness
Summary

The interviewee explains his training method, which involves multiple rounds of high-intensity exercises with short rest periods. He recommends resting for one to three minutes between rounds and doing up to six rounds in one training session.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The podcast discusses improving garden effectiveness by bringing in nutrients and dealing with waste.
3:14:21 - 3:21:10 (06:48)
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Gardening
Summary

The podcast discusses improving garden effectiveness by bringing in nutrients and dealing with waste. A suggestion is made to progress by doing a higher amount of work every week or by adding a round, where the quality of the work decreases but it challenges the buffering system in a positive way.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
For high-level athletes, low-load training can improve performance, while for others, it is best to incorporate at least 20-30 minutes of steady-state exercise once a week for any training goals outside of specific scenarios.
3:21:11 - 3:30:25 (09:13)
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Athletic Training
Summary

For high-level athletes, low-load training can improve performance, while for others, it is best to incorporate at least 20-30 minutes of steady-state exercise once a week for any training goals outside of specific scenarios. Short circuits with exercises like farmer's carries can also be effective with minimal downtime.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
This podcast episode offers a comprehensive endurance training program that combines different elements of endurance for a stronger and faster performance in running, cycling, or swimming.
3:30:25 - 3:39:43 (09:18)
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Endurance training
Summary

This podcast episode offers a comprehensive endurance training program that combines different elements of endurance for a stronger and faster performance in running, cycling, or swimming.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The key to preparing for a half marathon involves dividing your training into two parts- 70% will cater to improving the specific event running and the remaining 30% will help in overall fitness.
3:39:43 - 3:45:59 (06:15)
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Half Marathon
Summary

The key to preparing for a half marathon involves dividing your training into two parts- 70% will cater to improving the specific event running and the remaining 30% will help in overall fitness. Focusing only on long steady state runs is a mistake that most runners make and that it is important to work on building one's speed and stamina for better results.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab
The Neural Network Newsletter provides monthly summaries of Huberman Lab podcast episodes and highlights specific protocols discussed, completely free of cost.
3:46:00 - 3:49:23 (03:23)
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Huberman Lab
Summary

The Neural Network Newsletter provides monthly summaries of Huberman Lab podcast episodes and highlights specific protocols discussed, completely free of cost.

Episode
GUEST SERIES | Dr. Andy Galpin: How to Build Physical Endurance & Lose Fat
Podcast
Huberman Lab